The concept of "Mrs." as a title of address before a woman's name is
an aspect of English Language.
"Mrs." is almost never used in ASL. If for whatever reason you
feel you need to express the concept of "Mrs." just spell it. (Don't
add the period.)
See:
"Titles of Address"
Also see:
"Dear"
Also see: "Name Signs"
You can learn
American Sign Language (ASL) online at American Sign Language University ™
ASL resources by Lifeprint.com © Dr. William Vicars