Can also mean main / discipline / field / line of work / career / profession
The sign for MAJOR is produced with "B" hands. Your non-dominant hand's palm faces to the right and your dominant hand's palm faces to the left. Only the dominant hand moves forward off the non-dominant hand.
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Sample sentence: What is your major?
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Also see:
MAJORITY
WORK
DEPARTMENT
BUSINESS
ROLE
OFFICE
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